Human Sera
Cayman Chemical LomerIzInhydrochlorIde 100mg
A voltage-dependent calcium channel blocker; inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons (IC50s = 1.9 and 4 μM, respectively); inhibits vasoconstriction induced by potassium chloride, 5-HT, or vasopressin in isolated rat basilar arteries at 1 μM; reduces neurotoxicity induced by glutamate, NMDA, or kainate in rat retinal primary cell cultures at 1 μM; reduces retinal damage in a rat model of retinal ischemia-reperfusion injury at 1 mg/kg
AdipoGen BioStab Antibody Stabilizer
Free or conjugated antibodies are often used in immunoassays, either in the system specific detector antibody plus streptavidin-HRP or in the system analyte-specific antibody plus species-specific antibody-HRP-conjugate. Both systems allow a high flexibility at lower costs. BioStab Antibody Stabilizer dramatically extends the life of your valuable antibodies, allowing much more consistent results over extended periods of time compared to daily prepared dilutions. BioStab Antibody Stabilizer can be used in ELISA, Western Blotting, Immunohistochemistry and any other applications which require marker or biotinylated antibodies. It is supplied as a ready-to-use solution for dilution of antibodies. This stabilizer contains a minimum amount of a surfactant. The stabilizer is free of any protein to minimize potential unspecific interactions. The method below is strongly recommended for standard assay procedures and reduces loss of valuable conjugates and assay-to-assay variations.
Cayman Chemical IrInotecnhydrochLRIde hyd 50mg
A derivative of the alkaloid camptothecin that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I; demonstrates a broad spectrum of antitumor activity against metastatic colorectal cancer, small cell lung cancer, and several other solid tumors
Cayman Chemical LeupeptInhemIsulfate 100mg
A reversible inhibitor of cysteine, serine, and threonine proteases; inhibits cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 μM), and kallikrein (Ki = 19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin
Cayman Chemical MadecasosIde 50mg
A natural triterpenoid with a wide range of reported anti-inflammatory, wound healing, and antioxidant activities; suppresses LPS-induced TNF-α production via inhibition of ERK, p38, and NF-κB activity
Cayman Chemical TrIfloxystrobIn 100mg
A fungicide; inhibits the growth of R. solani isolates from sugar beet crops (EC50s = 0.14-823.54 μg/ml); inhibits mycelial growth of C. gloeosporioides when used in combination with tebuconazole from 100-1,000 ppm; toxic to various aquatic species, including R. arenarum, P. santafecinus, E. bicolor, and L. latrans tadpoles (LC50s = 0.22, 0.14, 0.1, and 0.26 mg/L, respectively); reduces mobility of tadpoles and decreases predation of trifloxystrobin-exposed, but not non-exposed, tadpoles by eels
Cayman Chemical trns-ZeatIn 50mg
A cytokinin plant growth regulator; binds to AHK3 (KD = 1.3 nM); increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner; increases callus growth and shoot formation in N. tabacum calluses at 5 and 50 µM; reduces production of ROS induced by Aβ25-35 in PC12 cells at 25-100 µM; scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice at 1.5, 3, and 4.5 mg/kg per day
Cayman Chemical Obatoclaxmesylate 50mg
An antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd ~500 nM); prevents interaction of these pro-survival proteins with Bax or Bak, inducing apoptosis; also induces autophagy in mouse embryo fibroblasts and in HeLa cell
Cayman Chemical Maltotetraose 50mg
A tetrasaccharide; increases the α-amylase synthesis rate in B. stearothermophilus three-fold greater than sucrose or glucose when used at at 0.1 mM; inhibits the growth of E. carotovora in a cylinder-agar plate assay at 750 μg/ml; inhibits TNF-α-induced expression of ICAM-1 in MOVAS-1 mouse VSMCs
Cayman Chemical 2hydroy PalmITC ACD mthy 50mg
A hydroxy fatty acid methyl ester; a minor component in essential oils of P. sylvestris and B. javanica extracts